Unknown attackers strike in their pursuit of Frankenstein and Lilja, so they look for help underwater only to find a powerful creature who has her own dark means of survival.

Mike Mignola, Christopher Golden, Tom Sniegoski, and Peter Bergting return to the New World that Hellboy and the B.P.R.D. gave their lives to save.

Continues the Hellboy universe story post B.P.R.D.